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刘炬教授课题组在Circulation Research发表微血管研究最新成果

jinri,dianjingpingtaidiyifushuyiyuan(shandongshengqianfoshanyiyuan)liujujiaoshouketizuzaijingdianqikancirculation research(yingxiangyinzi: 14.467)fabiaoleyanjiuxinglunwen“aberrant activation of notch1 signaling in glomerular endothelium induces albuminuria”。gailunwenbeixuanweicirculation researchzuijinyiqidefengmianlunwen。

danbainiaobujinshigezhongshenzangjibingdezhongyaozhenduanzhibiao,danbainiaodechuxianyehuijiasushenzangsunshanghejibingjinzhan。shenxiaoqiuneipixibaoshishenxiaoqiuguolvpingzhangdediyidaofangxian,qifenzishaihedianheshaizuoyongnengfangzhidanbaizhidengdafenzicongxueyezhongyichu。notchxinhaotonglucanyudiaokongshenxiaoqiuguolvpingzhang,danqizaineipixibaozhongdezuoyonghaibuqingchu。gaiyanjiugoujianlexueguanneipixibaoteyixingdetiaojianxingheyoudaoxingnotch1baoneiduan(nicd1)zhuanjiyinxiaoshumoxing,congershixianlezaichengnianxiaoshuneipixibaozhongjihuonotchxinhaotonglu。nicd1guobiaodadechengnianxiaoshuchuxianlexianzhudedanbainiaozhengzhuang,jinyibuyanjiufaxiannotchxinhaotonglujihuonengxianzhujiangdishenxiaoqiuneipixibaozhongnianfulianjiedehexinfenzive-cadherindebiaoda,shenggaoshenxiaoqiuneipixibaotongtouxing。tongshi,notchxinhaotonglujihuohoushenxiaoqiuneipixibaodetangechengfenjianshao,zheikenengyunianfulianjiedepohuaiyouguan。gaiyanjiujieshilenotchxinhaotonglujihuosunshangshenxiaoqiuneipixibaonianfulianjiedaozhidanbainiaodefenzijizhi,weidanbainiaodefashengjizhiyanjiutigonglexindesilu。

电竞平台刘炬教授为本文通讯作者,电竞平台为本文第一完成单位。电竞平台第一附属医院(山东省千佛山医院)医学研究中心和微血管医学研究所的研究生李利群和副研究员刘强为本文共同第一作者。该研究得到了国家自然科学基金、电竞平台学术提升计划(2019QL014)和山东省泰山学者工程的资助。


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